It is a great pleasure to invite you to our 5^th International Symposium on “Multivalency in Chemistry and Biology“ which will take place from September 30^th until October 2^nd, 2019 at the Freie Universität Berlin to meet with our scientists and students in the collaborative research center SFB 765 to discuss and develop new interactions and strengthen existing ones.

This symposium is part of our Collaborative Research Center SFB 765 „Multivalency as chemical organization and action principle: new architectures, functions and applications“ (www.sfb765.de) with a major focus on multivalent interactions with biological surfaces. We offer several exciting invited lectures on multivalency-driven architectures, functions and action principles from different research fields for inspiration and discussion of future projects. Additionally, the SFB will present its collaborative projects, and review the results from the last three funding periods (2008-2019).

The symposium will serve as a platform to discuss ideas and concepts in the presented lectures and poster contributions. Our particular aim is to foster a critical evaluation and discussion and to promote new concepts and applications for multivalent interactions. The Freie Universität Berlin as one of the German Excellence Universities will serve as a prominent historical location on the campus in Dahlem with a high density of scientific activities and industrial collaborations in various research areas.In detail, the symposium covers three major research topics from biophysics, chemical biology, supramolecular chemistry and nanoscience including:

1. Supramolecular Nanosystems
2. Multivalent Biosystems
3. Mucus Hydrogels

We are looking forward to welcome you in Berlin.

Prof. Dr. Rainer Haag,
Spokesperson of the SFB 765

Flyer

Registration

Program

Monday, September 30^th, 2019

13:00 REGISTRATION

14:00 Welcome and Highlights of the SFB765
Rainer Haag | Freie Universität Berlin

Session: Supramolecular Nanosystems

14:15 Multivalent Supramolecular Nanosystems
Takuzo Aida | University of Tokyo, JP

15:00 Multivalent Crown Ethers: From Fundamental Studies of Multivalency to Supramolecular Polymers and Gels
Christoph Schalley | Freie Universität Berlin

15:30 Self-Assembly of Functional Nanosystems Using Multivalent Interactions
Leonard Prins | University of Padova, IT

16:00 Multivalency and Multiplexing in Polymersomes Design: Toward the Design of Precision Nanomedicines
Giuseppe Battaglia | University College London, UK

16:30 COFFEE BREAK

17:00 Honorary Doctorate Ceremony

Welcome
Günter M. Ziegler | President of Freie Universität Berlin

Laudatio
Frank Würthner | University of Würzburg

Award of the Honorary Doctorate Certificate to Prof. Egbert W. Meijer | University of Eindhoven, NL
by Matthias Rillig | Dean of the Faculty Biology, Chemistry, Pharmacy

Award Lecture
Functional Supramolecular Materials and Systems

18:25 Welcome Reception in the Foyer

TUESDAY, OCTOBER 01^st, 2019

Session: Multivalent Biosystems

08:30 Multivalent Polymer Micelles
Kazunori Kataoka | University of Tokyo, JP

09:15 Multivalent Polyanions as Protein Inhibitors
Jens Dernedde | Charité-Universitätsmedizin Berlin

09:45 Multivalent Glyco Mimetics
Kamil Godulda | University of California San Diego, USA

10:15 COFFEE BREAK

10:45 Multivalent Membrane-Interaction of SV40
Helge Ewers | Freie Universität Berlin

11:15 Multivalent Supramolecular Irreversible Inteactions with Viruses
Francesco Stellacci | EPFL, CH

11:45 Elucidating Ligand Recognition and Allostery in Multivalent Systems
Bettina Keller | Freie Universität Berlin

12:15 LUNCH BUFFET & POSTER SESSION

13:30 Multivalent Interactions with Modified Nucleic Acids
Jesper Wengel | Syddansk Universitet, DK

14:15 Multivalent Ligands Based on DNA-Scaffolds
Oliver Seitz | Humboldt-Universität zu Berlin

14:45 10 SPEED LECTURES from selected posters

15:45 COFFEE BREAK & POSTER SESSION

17:30 Multivalency in Polyanion-Protein Interactions
Matthias Ballauff | Helmholtz-Zentrum Berlin

18:00 Polyanion Inhibitors Against Heparins, Polyphosphate and Nucleic Acids
Jayachandran Kizhakkedathu | University of British Columbia, CA

19:00 CONFERENCE DINNER

WEDNESDAY, OCTOBER 02^nd, 2019

Session: Mucus Hydrogels

08:30 Finding a Niche: Microbial Colonization of Host Mucosal Barriers
Katharina Ribbeck | Massachusetts Institute of Technology, USA

09:15 Probing Virus-Receptor Interactions at Interfaces and within Hydrogels
Stephan Block | Freie Universität Berlin

09:45 Mysteries of Mucus Physical Properties
Michael C. Rubinstein | Duke University, Durham, USA

10:30 COFFEE BREAK

11:00 Development and Characterization of Mucolytic Polymer Systems for Treatment of Severe Obstructive Lung Disease
Daniel Lauster | Freie Universität Berlin

11:30 Modelling and Overcoming Cellular and Non-Cellular Elements of Mucosal Barriers
Claus-Michael Lehr | Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Universität des Saarlandes, Saarbrücken

12:00 LUNCH BUFFET & POSTER SESSION

13:30 Penetration of Mucin Gels by Molecules
Oliver Lieleg | Technische Universität München

14:00 Mucus Hydrogel Barriers
David Thornton | University of Manchester, UK

14:30 COFFEE BREAK

Georg-Manecke-Award 2019
15:00 Welcome and Introduction by Brigitte Voit | Leibnitz-Institut für Polymerforschung, Board of the Georg-Manecke-Preis Committee

15:15 Laudatio and Award Ceremony by Prof. Andreas Fery | Leibnitz-Institut für Polymerforschung Dresden
15:20 Lecture of the Awardee
Dr. Julian Thiele | Leibnitz-Institut für Polymerforschung Dresden
Polymer Microgels as Tailored Platform for Cell-Free Biosynthesis

15:40 POSTER PRIZES & CLOSING REMARKS
Rainer Haag | Freie Universität Berlin

15:45 End of Symposium