Self-assembly of pre-organized subunits with a concave overall shape is an effective strategy for the synthesis of supramolecular capsules. We report the synthesis of a cavitand-based hexameric capsule held together solely by 12 robust [N⋅⋅⋅I+⋅⋅⋅N] halogen bonds and its characterization in solution and in the gas phase via 1H NMR spectroscopy, diffusion-ordered nuclear magnetic resonance spectroscopy (DOSY), and electrospray ionization mass spectrometry. The [N⋅⋅⋅I+⋅⋅⋅N] halogen-bonded hexameric capsule was efficiently synthesized from the isolobal metallosupramolecular Ag+ capsule by application of the [N⋅⋅⋅Ag+⋅⋅⋅N] → [N⋅⋅⋅I+⋅⋅⋅N] cation-exchange reaction.